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The TMJ Association is pleased to partner with Inspire to bring you the TMJ Cafe, a free online support network and discussion community for those with Temporomandibular Disorders (TMD). We invite you to meet others like you, share experiences and tips for getting through the day, and give and receive support.

Sustained and Repeated Mouth Opening Leads to Development of Painful Temporomandibular Disorders Involving Macrophage/Microglia Activation in Mice

Temporomandibular disorder (TMD) is a set of heterogeneous musculoskeletal conditions involving the temporomandibular joint (TMJ) and/or the masticatory muscles. Up to 33% of the population has had at least one symptom of TMD with 5-10% of them requiring treatment. Common symptoms include limited jaw movement, joint sound, and pain in the orofacial area. Once TMD becomes chronic, it can be debilitating with comorbidities that greatly reduce one's overall quality of life. However, the underlying mechanism of TMD is unclear due to the multicausative nature of the disease.

Prevalence of TMD in Sjӧgren Syndrome Patients

Sjӧgren's Syndrome seems to play a role in temporomandibular joint disorders.

Early Molecular Response and Microanatomical Changes in the Masseter Muscle and Mandibular Head After Botulinum Toxin Intervention in Adult Mice

The Botox-injected masseters had greatly increased expression of genes involved in muscle atrophy at the 1 week time point compared to the control side muscles. At the end of the study, 2 weeks after injection, the Botox-injected masseters were about 20% smaller than the control side masseters, and the Botox-side condyles had lost about 40% of relative bone area compared to the control side condyles.

Centralized Pain in TMD: Is It All in the Head?

We are pleased to introduce Sophia Stone, a new contributor to The TMJ Association, whose passion is to separate TMD fact from TMD fiction. Sophia has a background in medicine and research and can draw on her personal experience as a TMD patient.

The TMJ Association by Terrie Cowley


  • Mar 31, 2018

    On February 26, TMJA staff participated in the Friends of the National Institute of Dental and Craniofacial Research (NIDCR) Patient Advocacy Council (PAC), an umbrella group comprising non-profit organizations that work together to advance dental, oral,


  • Aug 24, 2017

    The TMJ Association is acting as the catalyst to develop the TMJ Patient RoundTable, a broad initiative to advance the interests of patients with temporomandibular disorders (TMD). It encompasses collaborations with all stakeholders and


  • Sep 9, 2016

    At the TMJ Association's Seventh Scientific Meeting, How Can Precision Medicine Be Applied to Temporomandibular Disorders and its Comorbities? , September 11-13, 2016, the Association recognized the following young investigators for their research in


  • Apr 1, 2016

    After President Obama submits his budget to Congress, the work of Representatives and Senators begins. It is at this time that we tell our elected officials what YOU, TMJ patients, need to have addressed. The past two months have been busy ones outsid


  • Dec 31, 2015

    My name is Jennifer Feldman, and I have suffered from TMJ dysfunction since age ten when I was in a car accident. All of my memories are attached to my condition. I remember sitting in waiting rooms for endless hours forming friendships with other patients who shared my pain.


  • Nov 11, 2015

    The Fall Giving Season Is Upon Us  If you are a government employee who understands the full impact of Temporomandibular Disorders (TMD) on individuals, their loved ones and society-at-large, please help us to continue to change the face


  • Dec 18, 2014

    We wish you and your family a joyous holiday season and healthy year ahead. Year's end is the time we reflect upon the past and look to the future. We are grateful for your moral and financial support that resulted in several impressive accomplishments in 2014.


  • Oct 23, 2014

    The TMJ Association is the only patient advocacy organization fighting for the best science that will lead to greater understanding of Temporomandibular and related disorders and safe and effective treatments. We need YOUR help in these efforts. Pleas


  • Oct 22, 2014

    Check Out These Two New Science Funding Opportunities Inspired by TMJA Advocacy 1. The Biology of the Temporomandibular Joint In our May 2013 issue of TMJ News Bites we reported that the NIH convened a round-table meeting to


  • Aug 20, 2013

    The TMJ Association (TMJA) is seeking candidates to serve on its Board of Directors. The TMJA aims to identify people with a passion and deep commitment to our mission−improve the quality of health care and lives of everyone affected by Temporom


  • Jul 31, 2013

    Each year we ask you to tell us what is on your mind regarding Temporomandibular Disorders and The TMJ Association's activities.  This year your participation is exceptionally important, because in the coming months we will be meeting to discuss


  • Jan 4, 2013

    On behalf of Members of The TMJ Association (TMJA) Board and the Scientific Advisory Board I wish you good health and happiness in 2013. What follows is a brief summary of how the TMJA has moved forward in 2012. The prominence of pain. As you know fro


  • May 24, 2011

    A few weeks ago I gave a presentation to the American Academy of Orofacial Pain at their annual meeting in Las Vegas. My husband Allen, also gave a presentation based upon his research utilizing systems approaches in hypertension research as an example


  • Jan 13, 2011

    I frequently think of all the people in my life who have been my support since my TMJ surgery, the so-called "wind beneath my wings." On December 27th I lost one of my staunchest supporters, my husband's mother. My own mother died when I


  • Jan 12, 2011

    Hyperacusis is defined as a collapsed tolerance to normal environmental sounds. Following jaw surgery, for about a year I experienced hyperaccusis. The slightest sound was painful to the point of tears. We don't often hear this symptom fr


  • Jul 14, 2010

    The TMJ Association (TMJA) is interested in attracting volunteers to serve in an advisory capacity to the organization to accelerate our efforts to expand awareness of temporomandibular joint and muscle disorders (TMJDs) among the public and profession


  • May 4, 2010

    In our effort to keep you abreast of articles of interest on many health care issues, I thought you would find the information from the National Institutes of Health Office of Research on Women's Health interesting. With the advent of brain imaging


  • Jan 26, 2010

    I send hearty congratulations to Deanne, TMJA's project coordinator, and to Danny and Susan of 11th Hour Solutions and the rest of the team for the hard work they put into developing the 2010 TMJ Association website. I’m proud of their work and


©2014 The TMJ Association, Ltd. All rights
In Treating TMJ

To view or order a free booklet about TMJ Disorders, visit the National Institutes of Health website.

U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES
National Institutes of Health
National Institute of Dental and Craniofacial Research
Office of Research on Women's Health