The University of Maryland Dental School has completed recruitment for a clinical trial to see if the drug duloxetine (Cymbalta) relieves pain of temporomandibular joint dysfunction. Duloxetine is an antidepressant also approved by the United States Food and Drug Administration (FDA) for the treatment of chronic pain of diabetic nerves and fibromyalgia. If duloxetine has a therapeutic effect, it could be the basis for use in patients with painful temporomandibular disorders.
The study results are undergoing analysis, but safety results show minimal side effects. Results in abstract form will be distributed when available mid-2012.
Sponsor: Elli Lilly & Company
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