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Patient Bone-Related Safety of Botox® for Treatment of TMD

Karen Raphael, PhD, a long-time TMD researcher now at the New York University College of Dentistry, has provided the following commentary on the Susan Herring Botox® article, along with information on her plans for clinical studies of TMD patients who have been treated with Botulinum Toxin for TMD Pain.

Further Evidence that Botox® Injections Cause Bone Loss in the Jaw

An article published online in the journal Bone* by a team of French investigators confirms that injecting Botox® into jaw muscles leads to significant bone loss in adult rats.

MAPP Network Basic/Translational Science

The OPPERA study has demonstrated that pelvic pain is moderately associated with Temporomandibualr Disorders. Given this relationship we are publicizing this new NIH research opportunity.   The Multidisciplinary Approach to the Study of Chronic P

Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases

Its purpose is to expand contemporary, systematic research approaches to elucidate the role of immune system plasticity in health and in the pathogenesis of dental, oral, and craniofacial (DOC) diseases. The goal is to advance knowledge of the immunologi

Ethics of TMD Treatments

When we read an article by Drs. Kevin Reid and Charles Greene on the ethics of TMD treatment in the Journal of Oral Rehabilitation, we thought the message was so important that we asked them to write on this topic for our readers.

ASSOCIATED CONDITIONS

  • Oct 9, 2014

What Conditions May Overlap with TMD?

Scientists have found that 85% of patients with TMD also experience painful conditions in other parts of the body. These comorbid conditions include chronic fatigue syndrome, chronic headache, endometriosis, fibromyalgia, interstitial cystitis, irritable bowel syndrome, low back pain, sleep disorders, and vulvodynia. They are considered comorbid because they occur together more often than chance can explain. In addition, the conditions share other features. These findings are stimulating research into common mechanisms underlying all of these comorbid conditions. Indeed, other research indicates that TMD is a complex disease like hypertension or diabetes involving genetic,  environmental, behavioral, and sex-related factors. Note that many of the comorbidities mentioned are more prevalent or occur exclusively in women.

The following are health conditions that may co-exist with TMJ Disorders:

To call attention to these little understood pain conditions that primarily or exclusively affect women, The TMJ Association co-founded the Chronic Pain Research Alliance (CPRA) in 2009. CPRA is working to educate federal authorities and advance research to discover mechanisms common to these conditions and safe and effective treatments. As part of this effort, the CPRA has informational websites - www.ChronicPainResearch.org and www.EndWomensPain.org.

 


In Treating TMJ

To view or order a free booklet about TMJ Disorders, visit the National Institutes of Health website.

U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES
National Institutes of Health
National Institute of Dental and Craniofacial Research
Office of Research on Women's Health