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The Scoop on TMD Pharmaceuticals

Let's say the National Institutes of Health just handed us a multi-million dollar grant to get to the bottom of TMD and find a cure once and for all. I mean, we could start handing out heating pads left and right, but that kind of relief can only get us so far. Whenever I try a different form of therapy or medication, I like to think about the biology, right down to the cellular and molecular level. Why are the cells that make up my jaw region being such jerks?

Join Us AT TMJ Cafe

The TMJ Association is pleased to partner with Inspire to bring you the TMJ Cafe, a free online support network and discussion community for those with Temporomandibular Disorders (TMD). We invite you to meet others like you, share experiences and tips for getting through the day, and give and receive support.

Sustained and Repeated Mouth Opening Leads to Development of Painful Temporomandibular Disorders Involving Macrophage/Microglia Activation in Mice

Temporomandibular disorder (TMD) is a set of heterogeneous musculoskeletal conditions involving the temporomandibular joint (TMJ) and/or the masticatory muscles. Up to 33% of the population has had at least one symptom of TMD with 5-10% of them requiring treatment. Common symptoms include limited jaw movement, joint sound, and pain in the orofacial area. Once TMD becomes chronic, it can be debilitating with comorbidities that greatly reduce one's overall quality of life. However, the underlying mechanism of TMD is unclear due to the multicausative nature of the disease.

Prevalence of TMD in Sjӧgren Syndrome Patients

Sjӧgren's Syndrome seems to play a role in temporomandibular joint disorders.

Early Molecular Response and Microanatomical Changes in the Masseter Muscle and Mandibular Head After Botulinum Toxin Intervention in Adult Mice

The Botox-injected masseters had greatly increased expression of genes involved in muscle atrophy at the 1 week time point compared to the control side muscles. At the end of the study, 2 weeks after injection, the Botox-injected masseters were about 20% smaller than the control side masseters, and the Botox-side condyles had lost about 40% of relative bone area compared to the control side condyles.

Teshania's Story

  • Dec 15, 2015

My name is Teshania, and I would like to share my TMJ story. Back in May 2012, I felt like I had an ear infection but also severe pain in my jaw. The pain was so bad that I could not close my mouth completely. I would hear a lot of popping in my ear as well and could not understand what was going on. I tried to associate the symptoms with allergies by taking different types of allergy medications, but they did not work. To make a long story short, I ended up seeing six doctors, an ENT specialist, a dentist and an orthodontist. They prescribed Naproxen, Robaxin, Tramadol, and a muscle relaxer. I was even fitted for a night guard. Two doctors told me I would just have to live with it. As a military spouse rather than a veteran, I was denied physical therapy.

Since then, the jaw pain and most of the popping in my ear has gone away. I still live with a feeling of tightness in my jaw joint. It does get bad at night, but I just deal with it. I exercise, do jaw exercises, stretch daily, and avoid hard foods. Also, I'm working on a soft food/no sugar meal plan. A bad habit of cheek chewing and phone cradling may explain why the discomfort hasn't completely gone away. To help, I just purchased a gel beaded TMJ relief head wrap. 

Praying for a cure, I hope I don't have to live the rest of my life with this discomfort.  I wish the same for others who are dealing with this disorder. Thanks for listening. 

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Comments:

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cmmessin56 - Saturday, October 31, 2015
I just wanted to let you know I am a US Air Force Veteran. My TMJ problems began in the Military in 1984. Multiple surgeries both jaws and medically discharged in 1992. I am greatful that my condition is treted very well from the VA Dental Clinic. My first thing I did after discharge was to apply for benefits. I just wanted to make sure my TMJ eould be tsjen care, as I new it would be very costly. I do not know how You and Other TMJ sufferers handle the pain physically amd mentally. Without my TMJ Oral Surgery Department Staff, I literally do not know what and where i would be now. Take care!