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Migraine and Coronary Artery Disease: A Genetic Connection

There has long been as association between migraine headaches and vascular (blood vessel) dysfunction of some kind, underscored by epidemiological studies and other research. New evidence for a genetic connection now comes from the analysis of several large data sets of each condition based on Genome Wide Association Studies (GWAS).

Patients with Chronic Migraine More Likely to Suffer from TMD

In a recent study, researchers found that patients with chronic migraines which usually occur for more than 15 days a month are likely to experience three times more severe symptoms of Temporomandibular disorder (TMD) than patients with an episodic migraine.

Are you a TMD patient with Tinnitus?

It's a ringing sound, a buzzing, a hiss.... It can be soft or loud, intermittent or present all the time, affecting one ear or both. In whatever way it affects you, it's damned annoying, unpleasant, distracting. Indeed, it is considered the worst problem affecting human beings after pain and dizziness.

Repeated Injections of Botox into the Masseter Muscle... A Longitudinal Study

The authors of this study examined mandibular bone before and after subjects received Botox injections into each masseter muscle. These volunteers were healthy adults (22-48 years old), both male and female, who wanted injections to slim their faces.

Washington Post Article on TMD

The Washington Post recently featured an article on Temporomandibular Disorders. Below is an excerpt from that article and a link to the full story.

TMJA's 8th Scientific Meeting

  • Mar 1, 2017

TMJA celebrated its 8th biennial scientific meeting this fall provocatively challenging
scientists to answer, "How Can Precision Medicine Be Applied to Temporomandibular
Disorders and its Comorbidities?" For three days scientists from fields outside TMD,
as well as some of the leaders you have read about in these News Bites, addressed
this question from multiple points of view. To set the stage, National Institutes of Health
(NIH) spokespersons explained exactly what precision medicine was all about. It is the
attempt to customize healthcare, with medical decisions, practices, and/or
products being tailored to the individual patient
.

To achieve that goal, a major new program, the U.S. Precision Medicine Initiative,
under NIH leadership, has been launched to amass health data on a huge sample of
volunteers. No less than one million Americans--male, female, old, young, sorted by
race, ethnicity, geographic locale and socioeconomic status--will be recruited to work
with scientists to provide genetic information, electronic health records, and a range of
physiological, lifestyle and environmental data. This will take time, obviously, but the
experts say it is an effort that is doable now because of the rapid advances in
technology that make genome sequencing cheap and fast, the adoption of electronic
health records, and new techniques for gathering personal data on an individual using
sensors and devices that could be built into a smart phone app.

That said, attendees at the TMJA meeting heard speakers describe research on many
fronts. Among them: ways in which TMD patients with overlapping pain conditions may
be sorted into subsets with common characteristics that permit more selective targets
for treatment, new ways of delivering and testing drugs, further fine-tuning of chronic
pain pathways, more on interactions between the nervous and immune systems, and
new ways of modelling disease using stem cells. A summary of the meeting and
recommendations for future research will appear in  an upcoming issue of TMJ Science.

TMJ Disorders

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