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Repeated Injections of Botox into the Masseter Muscle... A Longitudinal Study

The authors of this study examined mandibular bone before and after subjects received Botox injections into each masseter muscle. These volunteers were healthy adults (22-48 years old), both male and female, who wanted injections to slim their faces.

Washington Post Article on TMD

The Washington Post recently featured an article on Temporomandibular Disorders. Below is an excerpt from that article and a link to the full story.

Partnering to Improve Chronic Pain Care

The National Institutes of Health (NIH) held three meetings this summer with the goal of developing the first public-private partnership (PPP) to develop safe and effective treatments for chronic pain, as well as new treatments for opioid addiction and overdose.

TMJ Patient RoundTable Project: Status Update

The TMJ Association is acting as the catalyst to develop the TMJ Patient RoundTable, a broad initiative to advance the interests of patients with temporomandibular disorders (TMD). It encompasses collaborations with all stakeholders and

Educational Brochures on Chronic Overlapping Pain Conditions

This brochure addresses what are Chronic Overlapping Pain Conditions (COPCs), how COPCs are diagnosed, the complexity of the chronic pain experience, and how to work with your health care provider to develop a treatment plan. It is available by postal ma

Estrogen Plunge Before Menstruation Linked to Migraine

  • Jan 26, 2017

Our 2016 TMJA online survey results show that 26% of respondents suffer from migraine
headaches; they are one of the overlapping chronic pain conditions associated with

Women who experienced a steeper decline in estrogen levels prior to menstruation
were more likely to experience migraines, researchers found.

In an analysis of data collected as part of the long-term longitudinal Study of Women's
Health Across the Nation (SWAN), migraineurs' urinary estrogens (E1c) declined in the
2 days before the period peak at a faster absolute rate than nonmigraineurs and at a
higher percent change than nonmigraineurs (40% versus 30%), Jelena Pavlovic, MD,
PhD, of the Albert Einstein College of Medicine in New York City, and colleagues
reported in Neurology. The study authors did not find significant differences in the
groups when they looked at absolute peak and daily hormone values, and they found
no significant differences in the time period around the ovulatory phase.

As part of a secondary analysis within the migraineurs' group, the authors determined
that hormone patterns were similar regardless of whether the woman had a migraine
that cycle. As a result, Pavlovic and her team formed a "two-hit" hypothesis in which
women with rapid estrogen level dips before menstruation are more sensitive to
migraine triggers, such as stress, lack of sleep or a glass of wine. It's a combination of
the estrogen drop and the additional triggers that result in a migraine.

Read full article at:

Overlapping Conditions


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In Treating TMJ

To view or order a free booklet about TMJ Disorders, visit the National Institutes of Health website.

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