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The TMJ Association is pleased to partner with Inspire to bring you the TMJ Cafe, a free online support network and discussion community for those with Temporomandibular Disorders (TMD). We invite you to meet others like you, share experiences and tips for getting through the day, and give and receive support.

Sustained and Repeated Mouth Opening Leads to Development of Painful Temporomandibular Disorders Involving Macrophage/Microglia Activation in Mice

Temporomandibular disorder (TMD) is a set of heterogeneous musculoskeletal conditions involving the temporomandibular joint (TMJ) and/or the masticatory muscles. Up to 33% of the population has had at least one symptom of TMD with 5-10% of them requiring treatment. Common symptoms include limited jaw movement, joint sound, and pain in the orofacial area. Once TMD becomes chronic, it can be debilitating with comorbidities that greatly reduce one's overall quality of life. However, the underlying mechanism of TMD is unclear due to the multicausative nature of the disease.

Prevalence of TMD in Sjӧgren Syndrome Patients

Sjӧgren's Syndrome seems to play a role in temporomandibular joint disorders.

Early Molecular Response and Microanatomical Changes in the Masseter Muscle and Mandibular Head After Botulinum Toxin Intervention in Adult Mice

The Botox-injected masseters had greatly increased expression of genes involved in muscle atrophy at the 1 week time point compared to the control side muscles. At the end of the study, 2 weeks after injection, the Botox-injected masseters were about 20% smaller than the control side masseters, and the Botox-side condyles had lost about 40% of relative bone area compared to the control side condyles.

Centralized Pain in TMD: Is It All in the Head?

We are pleased to introduce Sophia Stone, a new contributor to The TMJ Association, whose passion is to separate TMD fact from TMD fiction. Sophia has a background in medicine and research and can draw on her personal experience as a TMD patient.

Brenda's Story of Endless Referrals

  • May 13, 2015

In August of 2012, I started having pain and discomfort in my face and jaw. It got very bad quickly, and I couldn't open my mouth or talk. I went to my doctor who said I have a TMJ problem, "go see your dentist." I went to my dentist and he sent me to an orthodontist, who fitted me with a splint that provided some relief. When things didn't get much better I went to a physical therapist and that helped some. Then I stopped getting better, so he referred me to a pain management doctor, who referred me to an oral surgeon and a periodontist. The oral surgeon did a jaw joint wash out, which has not helped as of this writing.

So I went to my doctor, my dentist, an orthodontist, a physical therapist, a pain management doctor, an oral surgeon, counseling and a periodontist with no relief! X-rays and cat scans show nothing wrong. I have been told it is due to stress. I cannot eat anything that requires any chewing; it hurts to talk, laugh, smile, yawn, even kiss! I cannot live like this.

I have digested the fact that I will most likely live with this disorder the rest of my life. I just need to get this pain to a manageable level. I will be getting a new appliance in three weeks to help stop grinding and clenching, which aggravates the situation greatly. I hope to get some relief soon.

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