An ad hoc committee, under the auspices of the National Academies of Sciences, Engineering, and Medicine's Health and Medicine Division, has been convened to study temporomandibular disorders (TMD) in a project entitled From Research Discoveries to Clinical Treatment. The members will address the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMD, and burden and costs associated with TMD.
The members will identify approaches to advance basic, translational, and clinical research in the field. Their findings, conclusions, and recommendations will also inform development of policies related to evidence-based treatment and clinical management of TMD patients.
Specifically, the committee's task calls for members to:
Review and estimate the public health significance of TMDs, including prevalence, incidence, burden and costs; and review challenges to data collection and reliability.
Evaluate the evidence base for assessment, diagnosis, treatment, and management of acute and chronic TMD. Recognizing that TMDs are diverse and multifactorial conditions influenced by genetics, sex and gender, environmental, physiological, and psychological factors, this effort will:
Identify barriers to appropriate patient-centered TMD care, in the presence and absence of an evidence base, and strategies to reduce these barriers along the continuum of TMD pain. This effort will:
Review the state of science for TMD and provide an overview of basic, translational, and clinical research for TMD. This effort will:
Examine existing or emerging TMD animal models and their preclinical utility.
Identify gaps and opportunities in TMD research relating to central and peripheral mechanisms, genetic/epigenetic contributions, heterogeneity of molecular mechanisms, joint mechanics, neuroimmune processes, endocrine influences, role of the microbiome, and endogenous mechanisms of resilience.
Identify opportunities and challenges for development, dissemination, and clinical implementation of safe and effective clinical treatments for TMD, including pharmacological agents, regenerative medicine, behavioral interventions, and complementary and integrative approaches.
Identify scientific and clinical disciplines needed to advance TMD science and the development, dissemination, and implementation of safe and effective treatments; as well as strategies to enhance education and training in these disciplines.
Identify multidisciplinary/interdisciplinary research approaches necessary in the short-and long-term to advance basic, translational, and clinical TMD research and to improve the assessment, diagnosis, treatment, and management of TMDs.
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The first meeting of the Committee was held on Tuesday, January 29, 2019 at the National Academy of Sciences building in Washington, D.C.
Terrie Cowley, President and Co-Founder of The TMJ Association, was asked to address the meeting. Click here to view her presentation before the committee.
The next National Academy of Medicine meeting will be held on March 28 and 29 in Washington D.C. and will include an open session to the public both days. More details are available at: http://www.nas.edu/hmd/Activities/PublicHealth/TemporomandibularDisorders/2019-MAR-28.aspx